Allergic Rhinitis and Its Causes
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Alexander Chong asked:
Allergic rhinitis is an atopic disease, which is inherited from the parent. If both your parents have allergic rhinitis or other respiratory diseases such as asthma, tuberculosis, and emphysema, the probability that you have these kinds of respiratory diseases is 50%. If one of your parents has respiratory diseases, the probability that you inherit their diseases is 25%. If both of your parents do not have any respiratory diseases, your chances to have respiratory diseases are no more than 12.5%. Sometimes, what has happened during pregnancy can cause allergic rhinitis to the newly born baby. The immunological status of the mother during pregnancy may cause the newly born baby has allergic rhinitis. Pregnant mothers who are smoking, drinking coffee and alcohol usually have poor immunological status, which can also cause newly born infant has allergic rhinitis or other respiratory diseases. This is because all these acts can cause high IgE antibody level in umbilical blood. Apart that, using bottle-feeding to feed milk to infant, early introduction of several kinds of food and early exposure to certain allergens and pollutants can cause nasal allergy to the newly born infant.
Allergic rhinitis symptoms change with age. At the earlier stage, children are mostly sensitive to seasonal allergens. After they have grown older, they usually become sensitive to perennial allergens. Therefore, after they have got over the symptom that is caused by seasonal allergens, they may still keep on the symptoms due to the perennial allergens. When the children grow older, they may have higher risk to have bronchial hyperreactivity and asthma. 17 to 19% of them will have asthma after grow up. To protect them from getting asthma, perennial immunotherapy should be used at the early stage. Moreover, the risk of getting asthma does not depend to age when the allergic rhinitis started, family history of atopic disease, sex, severity of symptoms at the starting period and treatment.
Allergic rhinitis started when the atopic individual meets the antigens that are able to stimulate the IgE response. So, what are substances that can act as allergens? Allergens usually are airborne particles, which have molecular weight ranging from 30 to 40,000 daltons and also with diameter ranging from 2 to 60 µm. Most of them have diameter more than 15 µm, which can deposit onto the nasal, pharyngeal and ocular surface. Chemically, these particles are proteins, which link to some small unit of carbohydrate. Particles that have these kinds of characters are pollen, acarids, animal dandruff and fungi.
Pollens that are released from grams, weeds and trees during breeding season usually cause seasonal allergic rhinitis. Only light pollens that can be pollinated by wind can exist in air and cause a high natural exposure to the allergic rhinitis patient. The seriousness depends to the concentration of the pollens in the atmosphere. Individual with allergic rhinitis who lives in suburban area will be seriously affected by these seasonal pollens compared to the one who lives in city. Surrounding temperature also gives an impact to the pollens concentration in air. Usually, in warmer environment, plants release more pollens compared to cold environment. Most of the plants breed in late spring and summer that is the warmest season. Windy weather will cause the pollens scatter around in air and this will cause the most exposure to the allergic rhinitis patient. The better day is rainy day. Rain water can wash all the pollens in air and bring them down to the ground. Surrounding air becomes fresher and cleaner after raining.
The main culprit of the perennial nasal allergy is house-dust mites. The acarids that are commonly found in the house dust are Dermatophagoides pteronyssimus and farinae, Euroglyphus maynei and Blomia tropicalis. Substances that are directly responsible to the nasal allergy from these dust mites are their body and metabolic products. Usually, mites grow rapidly in damp and warm climate. Therefore, sensitization to acarids depends to where you are actually living. Nasal allergy for patients who live in tropical and equatorial regions have higher possibility causes by acarids because these regions climate is promote mites growth. House-dust mites grow at maximized concentration when surrounding humidity level is between 70 to 80 % and with the presence of high temperature. Nasal allergy symptoms will develop when the level of dust mite concentration reaches 2 µg/g in air. Conversely, in high mountains with dry and cold climate have lowest level of dust mites because this climate prevents the mite growth. Animals also are the other source of aeroallergens. These aeroallergens are present in the animal’s saliva, feces, urine and dandruff. Therefore, nasal allergy can be caused by domestic animals such as cat and dog and also wild rats and mice.
Air pollutants enhance the sensitization of the nasal allergy by the allergens. Air pollutants can be divided to two groups that are outdoor pollutants, which are released from industrial works, automobile exhaust and domestic heating, and indoor pollutants such as tobacco smoke, furnishings, wood and coal burning and heater. Chemically, air pollutants consist of oxides of nitrogen, sulfur dioxide, ozone, carbon monoxide and black smoke. How actually air pollutants enhance sensitization of nasal allergy is not completely clear. This may be due to air pollutants easily irritate the respiratory mucosa and make it prone to allergic sensitization. Air pollutants have negative impact to the nasal epithelium and ciliary beat, which are responsible to the clearance of allergens. Furthermore, some pollutants can enhance the releasing of the mediators that induce inflammation such as histamine, prostaglandins and leukotriene C-4.
Apart from that, some pollutants also can stimulate synthesis of the IgE antibody directly. When allergen binds two IgE molecules together on the mast and basophil cells surface, primary chemical mediator; histamine, will be released and it will cause nasal allergy. Therefore, we can affirm that allergens can easily enter into our blood stream through our nasal mucosal membrane if we have chronic inflammation, not enough IgA antibody, impaired ciliary beat and also with air pollutants around us. IgA antibody is very important to our body because it prevents allergens from penetrating through our nasal mucosal layer. Monounsaturated oleic acids, which can be found in cold-pressed extra virgin olive and coconut oil, hazelnut or filbert oil (or the whole nuts), green and ripe olives, and almonds can increase IgA antibody in our body. Besides oleic acids, vitamin A also can increase IgA antibody, which can be found in cod liver oil, pumpkin, cooked carrots, sweet potatoes/yams, squash and other yellow or orange vegetable.
References:
Passàli D, Mosges R. Consensus Conference of Allergic Rhinitis in Childhood. Allergy 1999;54 (Suppl 55):5–27.
Linna O, Kokkonen J, Lukin M. A 10-year prognosis for childhood allergic rhinitis. Acta Paediatr 1992;81:100–2.
Braham SS, Barrows AA, Decotiis BA, Settipane GA, Corrao WM. Airway hyperresonsiveness in allergic rhinitis. A risk factor for asthma. Chest 1987;01:671–4.
Pedvis S, Fox ZR, Bacal HL. Long-term follow-up of ragweed hay fever in children. Ann Allergy 1962;20:
569–77.
Ausdenmoore RW. Allergeni aerei e fattori ambientali. In Lawlor GJJr, Fisher TJ editors. Manuale di Immunolgia
e allergologia. Milano, Libreria Editrice Internazionale, 1990:50–62.
Taudorf E, Moseholm L. Pollen count, symptom and medicine score in birch pollinosis. A mathematical approach. Int Arch Allergy Appl Immunol 1988;86:225–33.
Krishna MT, Mudway IM, Kelly FJ, Frew AJ, Holgate ST. Ozone, airways and allergic airways disease. Clin Exp Allergy 1995;25:1150–8.
Konlee, Mark. “A Consumer’s Guide to Immune Restoration: The Search for ‘Th1′.” Positive Health News. Report No. 18. Spring 1999.
Allergic rhinitis is an atopic disease, which is inherited from the parent. If both your parents have allergic rhinitis or other respiratory diseases such as asthma, tuberculosis, and emphysema, the probability that you have these kinds of respiratory diseases is 50%. If one of your parents has respiratory diseases, the probability that you inherit their diseases is 25%. If both of your parents do not have any respiratory diseases, your chances to have respiratory diseases are no more than 12.5%. Sometimes, what has happened during pregnancy can cause allergic rhinitis to the newly born baby. The immunological status of the mother during pregnancy may cause the newly born baby has allergic rhinitis. Pregnant mothers who are smoking, drinking coffee and alcohol usually have poor immunological status, which can also cause newly born infant has allergic rhinitis or other respiratory diseases. This is because all these acts can cause high IgE antibody level in umbilical blood. Apart that, using bottle-feeding to feed milk to infant, early introduction of several kinds of food and early exposure to certain allergens and pollutants can cause nasal allergy to the newly born infant.
Allergic rhinitis symptoms change with age. At the earlier stage, children are mostly sensitive to seasonal allergens. After they have grown older, they usually become sensitive to perennial allergens. Therefore, after they have got over the symptom that is caused by seasonal allergens, they may still keep on the symptoms due to the perennial allergens. When the children grow older, they may have higher risk to have bronchial hyperreactivity and asthma. 17 to 19% of them will have asthma after grow up. To protect them from getting asthma, perennial immunotherapy should be used at the early stage. Moreover, the risk of getting asthma does not depend to age when the allergic rhinitis started, family history of atopic disease, sex, severity of symptoms at the starting period and treatment.
Allergic rhinitis started when the atopic individual meets the antigens that are able to stimulate the IgE response. So, what are substances that can act as allergens? Allergens usually are airborne particles, which have molecular weight ranging from 30 to 40,000 daltons and also with diameter ranging from 2 to 60 µm. Most of them have diameter more than 15 µm, which can deposit onto the nasal, pharyngeal and ocular surface. Chemically, these particles are proteins, which link to some small unit of carbohydrate. Particles that have these kinds of characters are pollen, acarids, animal dandruff and fungi.
Pollens that are released from grams, weeds and trees during breeding season usually cause seasonal allergic rhinitis. Only light pollens that can be pollinated by wind can exist in air and cause a high natural exposure to the allergic rhinitis patient. The seriousness depends to the concentration of the pollens in the atmosphere. Individual with allergic rhinitis who lives in suburban area will be seriously affected by these seasonal pollens compared to the one who lives in city. Surrounding temperature also gives an impact to the pollens concentration in air. Usually, in warmer environment, plants release more pollens compared to cold environment. Most of the plants breed in late spring and summer that is the warmest season. Windy weather will cause the pollens scatter around in air and this will cause the most exposure to the allergic rhinitis patient. The better day is rainy day. Rain water can wash all the pollens in air and bring them down to the ground. Surrounding air becomes fresher and cleaner after raining.
The main culprit of the perennial nasal allergy is house-dust mites. The acarids that are commonly found in the house dust are Dermatophagoides pteronyssimus and farinae, Euroglyphus maynei and Blomia tropicalis. Substances that are directly responsible to the nasal allergy from these dust mites are their body and metabolic products. Usually, mites grow rapidly in damp and warm climate. Therefore, sensitization to acarids depends to where you are actually living. Nasal allergy for patients who live in tropical and equatorial regions have higher possibility causes by acarids because these regions climate is promote mites growth. House-dust mites grow at maximized concentration when surrounding humidity level is between 70 to 80 % and with the presence of high temperature. Nasal allergy symptoms will develop when the level of dust mite concentration reaches 2 µg/g in air. Conversely, in high mountains with dry and cold climate have lowest level of dust mites because this climate prevents the mite growth. Animals also are the other source of aeroallergens. These aeroallergens are present in the animal’s saliva, feces, urine and dandruff. Therefore, nasal allergy can be caused by domestic animals such as cat and dog and also wild rats and mice.
Air pollutants enhance the sensitization of the nasal allergy by the allergens. Air pollutants can be divided to two groups that are outdoor pollutants, which are released from industrial works, automobile exhaust and domestic heating, and indoor pollutants such as tobacco smoke, furnishings, wood and coal burning and heater. Chemically, air pollutants consist of oxides of nitrogen, sulfur dioxide, ozone, carbon monoxide and black smoke. How actually air pollutants enhance sensitization of nasal allergy is not completely clear. This may be due to air pollutants easily irritate the respiratory mucosa and make it prone to allergic sensitization. Air pollutants have negative impact to the nasal epithelium and ciliary beat, which are responsible to the clearance of allergens. Furthermore, some pollutants can enhance the releasing of the mediators that induce inflammation such as histamine, prostaglandins and leukotriene C-4.
Apart from that, some pollutants also can stimulate synthesis of the IgE antibody directly. When allergen binds two IgE molecules together on the mast and basophil cells surface, primary chemical mediator; histamine, will be released and it will cause nasal allergy. Therefore, we can affirm that allergens can easily enter into our blood stream through our nasal mucosal membrane if we have chronic inflammation, not enough IgA antibody, impaired ciliary beat and also with air pollutants around us. IgA antibody is very important to our body because it prevents allergens from penetrating through our nasal mucosal layer. Monounsaturated oleic acids, which can be found in cold-pressed extra virgin olive and coconut oil, hazelnut or filbert oil (or the whole nuts), green and ripe olives, and almonds can increase IgA antibody in our body. Besides oleic acids, vitamin A also can increase IgA antibody, which can be found in cod liver oil, pumpkin, cooked carrots, sweet potatoes/yams, squash and other yellow or orange vegetable.
References:
Passàli D, Mosges R. Consensus Conference of Allergic Rhinitis in Childhood. Allergy 1999;54 (Suppl 55):5–27.
Linna O, Kokkonen J, Lukin M. A 10-year prognosis for childhood allergic rhinitis. Acta Paediatr 1992;81:100–2.
Braham SS, Barrows AA, Decotiis BA, Settipane GA, Corrao WM. Airway hyperresonsiveness in allergic rhinitis. A risk factor for asthma. Chest 1987;01:671–4.
Pedvis S, Fox ZR, Bacal HL. Long-term follow-up of ragweed hay fever in children. Ann Allergy 1962;20:
569–77.
Ausdenmoore RW. Allergeni aerei e fattori ambientali. In Lawlor GJJr, Fisher TJ editors. Manuale di Immunolgia
e allergologia. Milano, Libreria Editrice Internazionale, 1990:50–62.
Taudorf E, Moseholm L. Pollen count, symptom and medicine score in birch pollinosis. A mathematical approach. Int Arch Allergy Appl Immunol 1988;86:225–33.
Krishna MT, Mudway IM, Kelly FJ, Frew AJ, Holgate ST. Ozone, airways and allergic airways disease. Clin Exp Allergy 1995;25:1150–8.
Konlee, Mark. “A Consumer’s Guide to Immune Restoration: The Search for ‘Th1′.” Positive Health News. Report No. 18. Spring 1999.
Allergic Rhinitis – Symptoms and Treatment
Mihail Fortomas asked:
Allergic rhinitis, more commonly known as “hay fever,” happens when you breathe in something you are allergic to. The inside of your nose becomes inflamed or swollen.
When this happens, the body’s immune system overreacts to specific particles such as plant pollens, molds, dust mites, animal hair, industrial chemicals, tobacco smoke, foods, medicines, and even insect venom.
Allergic rhinitis affects 40 million people in the United States and is an extremely common condition, affecting approximately 20% of the population. While allergic rhinitis is not a life-threatening condition, complications can occur and the condition can impair one’s quality of life leading to a number of indirect costs. Recently, the total direct and indirect cost of allergic rhinitis was estimated at around $5 billion annually.
What are the symptoms of allergic rhinitis?
Signs of allergic rhinitis are similar to signs of a common cold. But, unlike symptoms for the common cold, allergic rhinitis can last for more than 8-10 days. Symptoms include: -stuffy or runny nose -sneezing -itchy or watery nose -itchy or watery eyes -coughing (caused by clear mucus running down the back of the throat) -feeling of a ‘permanent cold’ that never goes away -headaches and earache -constant sore throats and postnasal drip -sleep disturbances and snoring -loss of taste and smell -poor concentration
Children who have allergic rhinitis might have dark circles under their eyes known as Allergic shiners” (related to nasal congestion). They may also use either the palm or the back of their hand to push their nose up as they try to stop the itching (called the “allergic salute”).
What causes allergic rhinitis?
Like our previous discussion, allergic rhinitis is caused by substances that trigger allergies, called allergens. These allergens are found both indoors and outdoors. When allergic rhinitis is caused by common outdoor allergens, like mold or trees, grass and weed pollens, it is often referred to as seasonal allergies, or “hay fever.”
Allergic rhinitis may also be triggered by allergens found in your house like animal dander (tiny skin flakes and saliva), indoor mold, and cockroach or house dust mite droppings.
If you experience symptoms during spring, you may be allergic to tree pollens which we will discuss in detail further on.
To know for certain what causes your symptoms, an allergist or immunologist can perform skin tests to determine what you are allergic to.
What are my choices or treatment?
Over-the-counter antihistamines and nose sprays can help at first, but they can have a number of unpleasant side effects. These antihistamines can make you feel tired and drowsy while nasal sprays can make your stuffiness worse.
Doctor-prescribed nose sprays and antihistamines are different types of medication and are very helpful for controlling long-term symptoms. Some are safe for young children and all are safe for adults.
Consultation with an allergist will determine the medicine and treatment that is right for you.
Can I do anything to avoid getting allergic rhinitis? As prevention is worth a pound of cure, there are some things you can do in your house that might make your symptoms better if not avoid them altogether:
For those who have rhinitis, it may be best not to have pets. But if it cannot be helped, make sure to wash your pet (especially if hairy and furry) once a week. Keeping them out of the bedroom and off the furniture will help as well.
Put pillows and mattresses in sealed plastic covers that keep out dust mites, and wash sheets in hot water weekly. Washing machines at the local Laundromat will have hot enough water to kill the dust mites.
Keep windows closed. If possible, get an air conditioner and run a dehumidifier, so that there will not be so many pollens and molds getting in the house.
What are allergy shots?
For some patients, allergy shots, also known as immunotherapy, are very helpful, and safe. Allergy shots help how your body handles allergens by injecting into your body small amounts of the substances causing your allergy. Over the period of the therapy, your body will learn to accept the allergen without overreacting to it (which is the reason for the allergic reactions).
Your doctor may talk to you about allergy shots if your allergy symptoms are very bad and if they happen for most of the year. You can also consider this if you are constantly around the allergens (such as pollens and dust mites) and if in spite medicines, you are still symptomatic.
Allergic rhinitis, more commonly known as “hay fever,” happens when you breathe in something you are allergic to. The inside of your nose becomes inflamed or swollen.
When this happens, the body’s immune system overreacts to specific particles such as plant pollens, molds, dust mites, animal hair, industrial chemicals, tobacco smoke, foods, medicines, and even insect venom.
Allergic rhinitis affects 40 million people in the United States and is an extremely common condition, affecting approximately 20% of the population. While allergic rhinitis is not a life-threatening condition, complications can occur and the condition can impair one’s quality of life leading to a number of indirect costs. Recently, the total direct and indirect cost of allergic rhinitis was estimated at around $5 billion annually.
What are the symptoms of allergic rhinitis?
Signs of allergic rhinitis are similar to signs of a common cold. But, unlike symptoms for the common cold, allergic rhinitis can last for more than 8-10 days. Symptoms include: -stuffy or runny nose -sneezing -itchy or watery nose -itchy or watery eyes -coughing (caused by clear mucus running down the back of the throat) -feeling of a ‘permanent cold’ that never goes away -headaches and earache -constant sore throats and postnasal drip -sleep disturbances and snoring -loss of taste and smell -poor concentration
Children who have allergic rhinitis might have dark circles under their eyes known as Allergic shiners” (related to nasal congestion). They may also use either the palm or the back of their hand to push their nose up as they try to stop the itching (called the “allergic salute”).
What causes allergic rhinitis?
Like our previous discussion, allergic rhinitis is caused by substances that trigger allergies, called allergens. These allergens are found both indoors and outdoors. When allergic rhinitis is caused by common outdoor allergens, like mold or trees, grass and weed pollens, it is often referred to as seasonal allergies, or “hay fever.”
Allergic rhinitis may also be triggered by allergens found in your house like animal dander (tiny skin flakes and saliva), indoor mold, and cockroach or house dust mite droppings.
If you experience symptoms during spring, you may be allergic to tree pollens which we will discuss in detail further on.
To know for certain what causes your symptoms, an allergist or immunologist can perform skin tests to determine what you are allergic to.
What are my choices or treatment?
Over-the-counter antihistamines and nose sprays can help at first, but they can have a number of unpleasant side effects. These antihistamines can make you feel tired and drowsy while nasal sprays can make your stuffiness worse.
Doctor-prescribed nose sprays and antihistamines are different types of medication and are very helpful for controlling long-term symptoms. Some are safe for young children and all are safe for adults.
Consultation with an allergist will determine the medicine and treatment that is right for you.
Can I do anything to avoid getting allergic rhinitis? As prevention is worth a pound of cure, there are some things you can do in your house that might make your symptoms better if not avoid them altogether:
For those who have rhinitis, it may be best not to have pets. But if it cannot be helped, make sure to wash your pet (especially if hairy and furry) once a week. Keeping them out of the bedroom and off the furniture will help as well.
Put pillows and mattresses in sealed plastic covers that keep out dust mites, and wash sheets in hot water weekly. Washing machines at the local Laundromat will have hot enough water to kill the dust mites.
Keep windows closed. If possible, get an air conditioner and run a dehumidifier, so that there will not be so many pollens and molds getting in the house.
What are allergy shots?
For some patients, allergy shots, also known as immunotherapy, are very helpful, and safe. Allergy shots help how your body handles allergens by injecting into your body small amounts of the substances causing your allergy. Over the period of the therapy, your body will learn to accept the allergen without overreacting to it (which is the reason for the allergic reactions).
Your doctor may talk to you about allergy shots if your allergy symptoms are very bad and if they happen for most of the year. You can also consider this if you are constantly around the allergens (such as pollens and dust mites) and if in spite medicines, you are still symptomatic.
Common Causes For Seasonal Allergies
November 9, 2009 by admin
Filed under Diseases And Conditions
Chris Marshall asked:
Seasonal Allergies usually occur during spring, fall and summer. Winter is not a common time for Allergies because there are not as many plants in bloom during this time due to the cold weather. When plants bloom and flourish, so do seasonal Allergies but this does not mean that this allergy is caused mainly by plants. The weather can also play a big role in triggering seasonal allergies.
Seasonal Allergies Due To Pollen And Dust
Pollen is one of the main causes of seasonal Allergies as well as dust and mold spores. These are common occurrences during spring and summer as well as during fall. The pollen from plants can cause serious hay fever in some individuals who are highly sensitive to the allergens they contain. Pollen tends to become airborne when the right season comes and these cause allergic reactions in individuals.
There is actually little that you can do about being allergic to pollen, dust and mold spores. Seasonal Allergies are usually controlled and not eliminated with the use of antihistamines. Although, not all areas of the city may have pollen, mold spores or dust, chances are, whenever you go around the city, you will encounter airborne mold spores, pollen and dust separately. If you are sensitive to any of these allergens, then you are highly likely to have an allergic reaction.
What To Expect From Seasonal Allergies
Seasonal Allergies usually manifest themselves as sneezing, runny noses, itchy eyes and other allergic rhinitis symptoms. You might initially think that you have a cold but actually there is a great deal of difference between the two. Seasonal Allergies are usually not accompanied by fever whereas a cold is and a cold usually lasts for around 10 days compared to seasonal Allergies that last for as long as you are exposed to the allergens.
Seasonal Allergies also react well to antihistamines whereas colds to decongestants. Allergies that rely on seasons also occur during summer, spring and fall compared to a cold that usually occur during winter. Allergies are also dependent on the individual’s reaction to allergens while colds can be transmitted from one person to another.
As stated earlier, these kinds of Allergies react well to antihistamines. Some may need stronger medication to control but the key is to lessen your exposure to the allergens. Allergens updates are also posted by the government to help out those who are sensitive to hay fever and other allergens.
Seasonal Allergies usually occur during spring, fall and summer. Winter is not a common time for Allergies because there are not as many plants in bloom during this time due to the cold weather. When plants bloom and flourish, so do seasonal Allergies but this does not mean that this allergy is caused mainly by plants. The weather can also play a big role in triggering seasonal allergies.
Seasonal Allergies Due To Pollen And Dust
Pollen is one of the main causes of seasonal Allergies as well as dust and mold spores. These are common occurrences during spring and summer as well as during fall. The pollen from plants can cause serious hay fever in some individuals who are highly sensitive to the allergens they contain. Pollen tends to become airborne when the right season comes and these cause allergic reactions in individuals.
There is actually little that you can do about being allergic to pollen, dust and mold spores. Seasonal Allergies are usually controlled and not eliminated with the use of antihistamines. Although, not all areas of the city may have pollen, mold spores or dust, chances are, whenever you go around the city, you will encounter airborne mold spores, pollen and dust separately. If you are sensitive to any of these allergens, then you are highly likely to have an allergic reaction.
What To Expect From Seasonal Allergies
Seasonal Allergies usually manifest themselves as sneezing, runny noses, itchy eyes and other allergic rhinitis symptoms. You might initially think that you have a cold but actually there is a great deal of difference between the two. Seasonal Allergies are usually not accompanied by fever whereas a cold is and a cold usually lasts for around 10 days compared to seasonal Allergies that last for as long as you are exposed to the allergens.
Seasonal Allergies also react well to antihistamines whereas colds to decongestants. Allergies that rely on seasons also occur during summer, spring and fall compared to a cold that usually occur during winter. Allergies are also dependent on the individual’s reaction to allergens while colds can be transmitted from one person to another.
As stated earlier, these kinds of Allergies react well to antihistamines. Some may need stronger medication to control but the key is to lessen your exposure to the allergens. Allergens updates are also posted by the government to help out those who are sensitive to hay fever and other allergens.
Nasal Allergy: Allergic Rhinitis and Its Causes
May 30, 2009 by admin
Filed under Diseases And Conditions
Alexander Chong asked:
Allergic rhinitis is an atopic disease, which is inherited from the parent. If both your parents have allergic rhinitis or other respiratory diseases such as asthma, tuberculosis, and emphysema, the probability that you have these kinds of respiratory diseases is 50%. If one of your parents has respiratory diseases, the probability that you inherit their diseases is 25%. If both of your parents do not have any respiratory diseases, your chances to have respiratory diseases are no more than 12.5%. Sometimes, what has happened during pregnancy can cause allergic rhinitis to the newly born baby. The immunological status of the mother during pregnancy may cause the newly born baby has allergic rhinitis. Pregnant mothers who are smoking, drinking coffee and alcohol usually have poor immunological status, which can also cause newly born infant has allergic rhinitis or other respiratory diseases. This is because all these acts can cause high IgE antibody level in umbilical blood. Apart that, using bottle-feeding to feed milk to infant, early introduction of several kinds of food and early exposure to certain allergens and pollutants can cause nasal allergy to the newly born infant.
Allergic rhinitis symptoms change with age. At the earlier stage, children are mostly sensitive to seasonal allergens. After they have grown older, they usually become sensitive to perennial allergens. Therefore, after they have got over the symptom that is caused by seasonal allergens, they may still keep on the symptoms due to the perennial allergens. When the children’s age is increasing, they may have higher risk to have bronchial hyperreactivity and asthma. 17 to 19% of them will have asthma after grow up. To protect them from getting asthma, perennial immunotherapy should be used at the early stage. Moreover, the risk of getting asthma does not depend to age when the allergic rhinitis started, family history of atopic disease, sex, severity of symptoms at the starting period and treatment.
Allergic rhinitis started when the atopic individual meets the antigens that are able to stimulate the IgE response. So, what are substances that can act as allergens? Allergens usually are airborne particles, which have molecular weight ranging from 30 to 40,000 daltons and also with diameter ranging from 2 to 60 µm. Most of them have diameter more than 15 µm, which can deposit onto the nasal, pharyngeal and ocular surface. Chemically, these particles are proteins, which link to some small unit of carbohydrate. Particles that have these kinds of characters are pollen, acarids, animal dandruff and fungi.
Pollens that are released from grams, weeds and trees during breeding season usually cause seasonal allergic rhinitis. Only light pollens that can be pollinated by wind can exist in air and cause a high natural exposure to the allergic rhinitis patient. The seriousness depends to the concentration of the pollens in the atmosphere. Individual with allergic rhinitis who lives in suburban area will be seriously affected by these seasonal pollens compared to the one who lives in city. Surrounding temperature also gives an impact to the pollens concentration in air. Usually, in warmer environment, plants release more pollens compared to cold environment. Most of the plants breed in late spring and summer that is the warmest season. Windy weather will cause the pollens scatter around in air and this will cause the most exposure to the allergic rhinitis patient. The better day is rainy day. Rain water can wash all the pollens in air and bring them down to the ground. Surrounding air becomes fresher and cleaner after raining.
The main culprit of the perennial nasal allergy is house-dust mites. The acarids that are commonly found in the house dust are Dermatophagoides pteronyssimus and farinae, Euroglyphus maynei and Blomia tropicalis. Substances that are directly responsible to the nasal allergy from these dust mites are their body and metabolic products. Usually, mites grow rapidly in damp and warm climate. Therefore, sensitization to acarids depends to where you are actually living. Nasal allergy for patients who live in tropical and equatorial regions have higher possibility causes by acarids because these regions climate is promote mites growth. House-dust mites grow at maximized concentration when surrounding humidity level is between 70 to 80 % and with the presence of high temperature. Nasal allergy symptoms will develop when the level of dust mite concentration reaches 2 µg/g in air. Conversely, in high mountains with dry and cold climate have lowest level of dust mites because this climate prevents the mite growth. Animals also are the other source of aeroallergens. These aeroallergens are present in the animal’s saliva, feces, urine and dandruff. Therefore, nasal allergy can be caused by domestic animals such as cat and dog and also wild rats and mice.
Air pollutants enhance the sensitization of the nasal allergy by the allergens. Air pollutants can be divided to two groups that are outdoor pollutants, which are released from industrial works, automobile exhaust and domestic heating, and indoor pollutants such as tobacco smoke, furnishings, wood and coal burning and heater. Chemically, air pollutants consist of oxides of nitrogen, sulfur dioxide, ozone, carbon monoxide and black smoke. How actually air pollutants enhance sensitization of nasal allergy is not completely clear. This may be due to air pollutants easily irritate the respiratory mucosa and make it prone to allergic sensitization. Air pollutants have negative impact to the nasal epithelium and ciliary beat, which are responsible to the clearance of allergens. Furthermore, some pollutants can enhance the releasing of the mediators that induce inflammation such as histamine, prostaglandins and leukotriene C-4.
Apart from that, some pollutants also can stimulate synthesis of the IgE antibody directly. When allergen binds two IgE molecules together on the mast and basophil cells surface, primary chemical mediator; histamine, will be released and it will cause nasal allergy. Therefore, we can affirm that allergens can easily enter into our blood stream through our nasal mucosal membrane if we have chronic inflammation, not enough IgA antibody, impaired ciliary beat and also with air pollutants around us. IgA antibody is very important to our body because it prevents allergens from penetrating through our nasal mucosal layer. Monounsaturated oleic acids, which can be found in cold-pressed extra virgin olive oil, hazelnut or filbert oil (or the whole nuts), green and ripe olives, and almonds can increase IgA antibody in our body. Besides oleic acids, vitamin A also can increase IgA antibody, which can be found in cod liver oil, pumpkin, cooked carrots, sweet potatoes/yams, squash and other yellow or orange vegetable.
Allergic rhinitis is an atopic disease, which is inherited from the parent. If both your parents have allergic rhinitis or other respiratory diseases such as asthma, tuberculosis, and emphysema, the probability that you have these kinds of respiratory diseases is 50%. If one of your parents has respiratory diseases, the probability that you inherit their diseases is 25%. If both of your parents do not have any respiratory diseases, your chances to have respiratory diseases are no more than 12.5%. Sometimes, what has happened during pregnancy can cause allergic rhinitis to the newly born baby. The immunological status of the mother during pregnancy may cause the newly born baby has allergic rhinitis. Pregnant mothers who are smoking, drinking coffee and alcohol usually have poor immunological status, which can also cause newly born infant has allergic rhinitis or other respiratory diseases. This is because all these acts can cause high IgE antibody level in umbilical blood. Apart that, using bottle-feeding to feed milk to infant, early introduction of several kinds of food and early exposure to certain allergens and pollutants can cause nasal allergy to the newly born infant.
Allergic rhinitis symptoms change with age. At the earlier stage, children are mostly sensitive to seasonal allergens. After they have grown older, they usually become sensitive to perennial allergens. Therefore, after they have got over the symptom that is caused by seasonal allergens, they may still keep on the symptoms due to the perennial allergens. When the children’s age is increasing, they may have higher risk to have bronchial hyperreactivity and asthma. 17 to 19% of them will have asthma after grow up. To protect them from getting asthma, perennial immunotherapy should be used at the early stage. Moreover, the risk of getting asthma does not depend to age when the allergic rhinitis started, family history of atopic disease, sex, severity of symptoms at the starting period and treatment.
Allergic rhinitis started when the atopic individual meets the antigens that are able to stimulate the IgE response. So, what are substances that can act as allergens? Allergens usually are airborne particles, which have molecular weight ranging from 30 to 40,000 daltons and also with diameter ranging from 2 to 60 µm. Most of them have diameter more than 15 µm, which can deposit onto the nasal, pharyngeal and ocular surface. Chemically, these particles are proteins, which link to some small unit of carbohydrate. Particles that have these kinds of characters are pollen, acarids, animal dandruff and fungi.
Pollens that are released from grams, weeds and trees during breeding season usually cause seasonal allergic rhinitis. Only light pollens that can be pollinated by wind can exist in air and cause a high natural exposure to the allergic rhinitis patient. The seriousness depends to the concentration of the pollens in the atmosphere. Individual with allergic rhinitis who lives in suburban area will be seriously affected by these seasonal pollens compared to the one who lives in city. Surrounding temperature also gives an impact to the pollens concentration in air. Usually, in warmer environment, plants release more pollens compared to cold environment. Most of the plants breed in late spring and summer that is the warmest season. Windy weather will cause the pollens scatter around in air and this will cause the most exposure to the allergic rhinitis patient. The better day is rainy day. Rain water can wash all the pollens in air and bring them down to the ground. Surrounding air becomes fresher and cleaner after raining.
The main culprit of the perennial nasal allergy is house-dust mites. The acarids that are commonly found in the house dust are Dermatophagoides pteronyssimus and farinae, Euroglyphus maynei and Blomia tropicalis. Substances that are directly responsible to the nasal allergy from these dust mites are their body and metabolic products. Usually, mites grow rapidly in damp and warm climate. Therefore, sensitization to acarids depends to where you are actually living. Nasal allergy for patients who live in tropical and equatorial regions have higher possibility causes by acarids because these regions climate is promote mites growth. House-dust mites grow at maximized concentration when surrounding humidity level is between 70 to 80 % and with the presence of high temperature. Nasal allergy symptoms will develop when the level of dust mite concentration reaches 2 µg/g in air. Conversely, in high mountains with dry and cold climate have lowest level of dust mites because this climate prevents the mite growth. Animals also are the other source of aeroallergens. These aeroallergens are present in the animal’s saliva, feces, urine and dandruff. Therefore, nasal allergy can be caused by domestic animals such as cat and dog and also wild rats and mice.
Air pollutants enhance the sensitization of the nasal allergy by the allergens. Air pollutants can be divided to two groups that are outdoor pollutants, which are released from industrial works, automobile exhaust and domestic heating, and indoor pollutants such as tobacco smoke, furnishings, wood and coal burning and heater. Chemically, air pollutants consist of oxides of nitrogen, sulfur dioxide, ozone, carbon monoxide and black smoke. How actually air pollutants enhance sensitization of nasal allergy is not completely clear. This may be due to air pollutants easily irritate the respiratory mucosa and make it prone to allergic sensitization. Air pollutants have negative impact to the nasal epithelium and ciliary beat, which are responsible to the clearance of allergens. Furthermore, some pollutants can enhance the releasing of the mediators that induce inflammation such as histamine, prostaglandins and leukotriene C-4.
Apart from that, some pollutants also can stimulate synthesis of the IgE antibody directly. When allergen binds two IgE molecules together on the mast and basophil cells surface, primary chemical mediator; histamine, will be released and it will cause nasal allergy. Therefore, we can affirm that allergens can easily enter into our blood stream through our nasal mucosal membrane if we have chronic inflammation, not enough IgA antibody, impaired ciliary beat and also with air pollutants around us. IgA antibody is very important to our body because it prevents allergens from penetrating through our nasal mucosal layer. Monounsaturated oleic acids, which can be found in cold-pressed extra virgin olive oil, hazelnut or filbert oil (or the whole nuts), green and ripe olives, and almonds can increase IgA antibody in our body. Besides oleic acids, vitamin A also can increase IgA antibody, which can be found in cod liver oil, pumpkin, cooked carrots, sweet potatoes/yams, squash and other yellow or orange vegetable.
