Alien asked:

The word ‘allergic’ is often used loosely and has become almost a part of our general conversation. In a way it has become synonymous with ‘dislike’. Many ailments which cannot be immediately diagnosed are incorrectly attributed to allergy. Infact, allergy is an unusual response of the body caused by substances like foods, pollens, house dust, feathers, fungus, insecticides, drugs, and chronic infection.

The common allergic diseases are allergic rhinitis and hay fever, and the common cause is pollen. Allergy is due to abnormal antibodies of the IgE type which are formed only in some -susceptible individuals. Normally the antibodies are supposed to be protective. But the abnormal antibodies are fixed on special allergic cells called mast cells and on coming into contact with an allergen such as a pollen, release chemical agents such as histamine, serotonin, and slow-reacting substances. The release of these substances produce symptoms of allergy characterized by a running nose, itching, rash, and breathing difficulty.

Treatment

The management of allergic reactions includes specific treatment aimed at removing the cause, blocking allergic reaction by immuno-therapy, and symptomatic treatment. Some examples of allergen-avoidance are stopping use of such drugs, installation of air filters in air conditioners, keeping pets out of living room and removing dust collecting furniture and carpets.

Specific Treatment

Specific treatment consists of removal of the offending agents. This is done by ‘allergen testing’. Various extracts of possible offending agents are available and these are injected into the skin to detect the causative agent. However, in most cases it is difficult to identify the causative agent, but if it is found, desensitization of the individual can be carried out by injecting its doses. It has been found that through desensitization, the abnormal antibodies, that is, the IgE antibodies, are reduced or completely abolished, and protective antibodies, that is, the IgG anibodies are developed.

Symptomatic Treatment

The aim of symptomatic treatment is to check the release or antagonize the action of released chemical mediators of allergic reactions. The most important of these chemical mediators is believed to be histamine. For this reason antihistaminics are employed in almost all cases of allergy. Sometimes decongestants are combined with antihistaminics to enhance effects. Only in extremely severe cases are corticosteroids used.

Uses of Antihistaminics

Besides their use in allergy, antihistaminics are useful for prophylaxis and treatment of motion (travel) sickness and vomiting during pregnancy or following radiation. They are beneficial in the symptomatic treatment of Parkinsonism but ineffective in bronchial asthma. They are quite often used to treat common cold. In this condition anti-cholinergic effects of these drugs afford symptomatic relief by decreasing secretions of nose and respiratory passages.

Adverse Effects: The most common adverse effects are drowsiness and sedation which interfere with daytime activity, mental alertness, and reflex actions. Other side-effects include giddiness, ringing in the ears, weariness, fatigue, loss of appetite, nausea, vomiting, rapid pulse, a slight fall in BP, constipation, abdominal pain, dryness of mouth, urinary hasitancy and blurring of vision. Very high doses may induce fever. These adverse effects are more common in elderly people.

Precautions

Alcohol is forbidden with these drugs as sedation of a dangerous level may occur.

Driving and operating any kind of machine should be avoided after taking these drugs as they cause drowsiness.

If taken after a meal, the intensity of side-effects can be minimized.

Drugs containing chlorcyclizine and meclizine which are also antihistaminic, should not be self used by a pregnant woman. These may cause some adverse effects on the foetus.

Ointments containing these drugs should not be used for a prolonged period; allergic reactions have been found to be more common on local application of these drugs. (At times these anti-allergic drugs, when taken orally or more commonly, when applied on the skin, may cause allergic reaction. Is this not a paradox?)

Other Drugs for Symptomatic Treatment

Ketotifen (Ketovent, Ketotif)

This drug stabilizes the cell membranes of mast cells and thus prevents the release of histamine. Besides having antihistaminic properties, it is useful in preventing an attack of asthma. It does, however, cause drowsiness, a dry mouth, dizziness, nausea and weight gain.

Cromolyn Sodium (Ifiral, Fintal)

Used as eye drops (2%) in allergic conjunctivitis, nasal spray (2%) in allergic rhinitis and metered dose inhaler (1 to 2 mg/puff) in bronchial asthma.

Nedocromil

This drug is used 2 puffs, twice a day, in place of cromolyn.

Topical steroids like flunisolide (SYNTARIS) and budesonide (BUDECORT) are nasal spray.

Non-Sedative Antihistaminics for Symptomatic Treatment

These new generation anti-allergic drugs do not reach the brain and do not produce sedation (cetirizine causes some sedation) which is common adverse effects of all the drugs available in this group. These are therefore used more widely. They do not impair psychomotor activities such as driving and do not enhance effects of alcohol or diazepam. They are useful in allergic rhinitis, allergic conjunctivitis, urticaria, drug allergies and atopic eczema. They are not effective in motion sickness, vertigo and should not be used in pregnancy. These agents are less effective than older drugs in common cold.

Decongestants Used in Symptomatic Treatment

These agents reduce the swelling of mucous membranes (shrinking effect) in allergic diseases by constricting small blood vessels. Some drugs are used by mouth such as pseudoephedrine (PSEUDAFED 60 mg tab) and phenylpropanolamine. The latter is rarely used alone.

Mark Bevan asked:


About Hay Fever

In the various seasons (spring, summer, and fall) during the year, pollen grains are dispersed from trees, weeds, and grasses. These pollen grains travel on air currents to fertilize other plants. Inhaling pollen, in some people, can trigger seasonal allergic rhinitis which is also called pollen allergy or hay fever. In this condition the mucous membranes in the nasal passages inflame, which causes swelling, sneezing, itching, irritation and a runny nose.

Allergy seasons are :

May – July/August – Grass pollen: Feb – June – Tree pollen (depending on whether allergic to early or late flowering trees) August – September – Nettle/weed pollen

Hay fever symptoms can continue all the year round and may also occur from indoor allergens like house dust mites, pets and possibly indoor moulds.

Hay fever is actually an attempt by the body to rid itself of allergens but the immune system overreacts and releases chemicals which cause inflammation, causing:

Itchy, watery, red eyes Frequent sneezing Constantly dripping nose

Sufferers, when afflicted with this condition, have to struggle to breathe through their nose. Symptoms are often quite bad in young people and tails off in later years as the body adapts. Studies have shown that hay fever can severely affect the quality of life, disturb sleep patterns, impair daytime concentration and work performance.

What is pollen allergy?

Pollen once released from trees, weeds and grasses, ride on air currents with a mission to disperse and fertilize other plants. However, they rarely reach their targets. On the way they get into human noses and throats, triggering allergic reactions.

Pollen is one of the most pervasive things that can cause an allergy and cannot be avoided. Many allergy causing foods, drugs, or animals can be largely avoided but insects and household dust are inescapable. However, short of staying indoors, there is no foolproof method of evading windborne pollen. Nonetheless, ways have been established that help ease the symptoms of hay fever. Moreover, scientists are working to find better approaches to allergy treatment.

Research has helped provide a better understanding of the causes of allergy, improve the methods for diagnosing and treating allergic reactions and thereby eventually preventing them. The common signs and symptoms of pollen allergy are:

Sneezing, the most common, may be accompanied by a runny or clogged nose Itching eyes, nose, and throat Allergic shiners (dark circles under the eyes caused by restricted blood flow near the sinuses) The “allergic salute” (in a child, persistent upward rubbing of the nose that causes a crease mark on the nose) Watering eyes Conjunctivitis (is inflammation of the membrane that lines the eyelids, causing red-rimmed eyes)

In a pollen-sensitive person, as soon as the allergy-causing pollen lands on the mucous membranes of the nose, a chain reaction occurs that leads the mast cells in these tissues to release histamine. This potent chemical dilates the small blood vessels in the nose; causing the fluids to escape through the expanded vessel walls, which in turn results in swelling of the nasal passages as well as nasal congestion. On the other hand, histamine also causes itching, irritation, and excess mucus production. Similarly, other chemicals like prostaglandins and leukotrienes also contribute to allergic symptoms.

Some people with pollen allergy also develop asthma, a serious respiratory condition, which can eventually become chronic. Symptoms include coughing, wheezing and shortness of breath due to a narrowing of the bronchial passages and excess mucus production.

Mark Bevan asked:


About Hay fever and allergic rhinitis

Hay fever or seasonal allergic rhinitis, generally results from airborne substances such as pollen that tend to easily enter the human body through the nose, sinus, throat and eyes, into the upper respiratory system where it forces the body to produce antibodies. These antibodies release histamine, the main culprit, which irritates the nasal passages, producing typical hay fever symptoms.

The name ‘hay fever’ is highly misleading, because symptoms occur all year round and not particularly in the autumn months when hay is gathered; moreover, it never includes fever. Most common of all allergic diseases, almost 15% of the world population suffers from this condition. Symptoms mostly appear in childhood first and then lessen as they age but this may not always be the case. It occurs all year round and may be caused by things such as house dust mites and pets. However, the predominant allergens keep changing from time to time.

Causes and symptoms of hay fever

Any substance can cause an allergy but hay fever is primarily caused by proteins. Commonly, hay fever is the direct result of an allergic person coming in repeated contact with plant protein. Flowering plants rarely cause allergies, however, the common trees, grasses, and weeds produce extremely small, light, dry protein particles which are called pollen. Spread by wind, these pollen particles are the male *** cells of the plant that are exceptionally minute in nature.

Although, usually invisible when airborne, pollen is a potent allergy stimulator. It has a tendency to lodge itself in the nasal lining tissues (also called the mucus membranes) as well as in other parts of the respiratory tract where it instigates allergic responses that can sometimes be serious. Since, a tendency to suffer allergies is often hereditary; an individual’s genetic makeup programmes him to be allergic, mostly from birth. The most common causes of hay fever are:

Tree pollen such as elder, elm, hazel and birch(spring) Grass pollen (summer) Mugwort and hybrids such as chrysanthemum (autumn) House dust mites and mould fungus

Symptoms of hay fever generally include:

Nasal congestion Clear runny nose Sneezing Itching of the nose and eyes Excessive tear production Postnasal drip that may result in cough Loss of the sense of smell Occasional loss of sense of taste Nose bleeds in severe conditions Allergic conjunctivitis (inflammation of the white portion of the eyes)

These allergic symptoms may sometimes become severe to an extent where they start to interfere with a person’s quality of life as well as overall health.

Hay fever bands

Hay fever bands are eco-friendly and are particularly liked by people who are health conscious and prefer to stay away from prescription medications as far as possible. This is a 100% safe and a viable alternative method that helps treat the condition without consuming drugs or chemicals.

A hay fever band uses the popular acupressure technique, embracing traditional Chinese healing methods to provide complete natural relief from the symptoms of hay fever. This band can be conveniently used by both adults and children over 3 years of age. Since, it is completely natural, the hay fever band does not cause drowsiness or have any kind of side-effects. Hay fever bands are completely drug free.

Pollen allergy

Plants produce pollen in order to reproduce. Plain-looking plants produce pollen that is generally responsible for causing allergic reactions. Unfortunately, too much pollen in the air can cause problems if you are sensitive to it.

Pollen allergy is most commonly caused by germinating plants like juniper and birch trees, as well as flowers, grass, grains, and common weeds like ragweed. If you shake a plant in germination, the cloud of powder that appears is the pollen that is capable of causing allergies.

Peter sams asked:


What are Allergies?

Allergies are abnormal immune system reactions to things that are typically harmless to most people. When you’re allergic to something, your immune system mistakenly believes that this substance is harmful to your body. (Substances that cause allergic reactions, such as certain foods, dust, plant pollen, or medicines, are known as allergens.)

Types of Allergies

1) Dust Mite Allergy-A dust mite allergy is an allergic reaction to a microscopic organism that lives in the dust that is found in most buildings and houses. Dust mites are a common cause of perennial allergic rhinitis. Dust mite allergy usually produces symptoms similar to pollen allergy and also can produce symptoms of asthma.

2) Corticosteroids — These anti-inflammatory agents are used to treat the itching and swelling associated with a variety of allergic disorders. The most commonly used forms are corticosteroid nasal sprays for allergic rhinitis and sinusitis (such as Flonase, Nasalide, Nasocort, Nasonex, Rhinocort), over-the-counter topical corticosteroid creams for hives, dermatitis, and insect sting reactions, and inhaled corticosteroids for asthma. Oral or injected corticosteroids are used less frequently for more severe cases of asthma, dermatitis, or other allergic reactions.

3) Epinephrine — Epinephrine (adrenalin) is used for emergency treatment in cases of anaphylaxis due to insect sting, food, or drug allergies. It is most commonly administered with a device called an EpiPen, which is a self-injectable shot of epinephrine. Epinephrine constricts the small blood vessels in the skin and mucous membranes, which increases blood pressure and heart rate back to normal levels. Epinephrine also is an antihistamine.

4) Immune complex allergies-Medication allergies are often type-III reactions. Foreign substances in the blood – such as medication – bond with antibodies, and then with the blood vessel walls in the smaller blood vessels, for instance, in the skin or kidneys. This leads to local inflammation, for instance, a skin rash, often in conjunction with haemorrhaging, skin damage, and itching.

5) Mold Allergy-A person can develop an allergy to the molds and yeasts that are commonly found indoors and outdoors. This eMedTV segment offers an in-depth look at the specific types of molds that cause allergies, as well as several ways to prevent mold allergy.

Symptoms Of Allergy

1) Tingling in the mouth

2) Hives, itching or eczema

3) Swelling of the lips, face, tongue and throat, or other parts of the body.

4) Watering eyes.

5) Cramps

6) Vomiting

7) Diarrhea

Cure for Allergies

1) Vacuuming the Right Way-If the carpet can’t be replaced by a solid surface such as linoleum or hardwood, then it must be cleaned thoroughly and frequently. Also remember to vacuum upholstered furniture, draperies, and other fabric items that cannot be washed, removed, or replaced. The trouble with vacuuming is that the allergenic dust mite and mold particles become airborne during the process. Dust mite particles can remain airborne for about 15 minutes and be redistributed throughout the home environment. Allergic persons clearly should not be doing The vacuuming and should also stay out of the area until the dust particles resettle

2) . Antihistamines- are used to relieve or prevent the symptoms of allergic rhinitis (hay fever) and other allergies. Antihistamines prevent the effects of histamine, a substance produced by the body during an allergic reaction. Antihistamines come in tablet, capsule, liquid, or injection form and are available both over-the-counter and by prescription.